Introduction Drowning represents a critical public health issue, causing approximately 236,000 deaths annually worldwide, making it the third leading cause of death from unintentional injuries globally. In the United States, the average number of deaths due to unintentional drowning exceeds 4,000 per year, with specific populations, such as children aged 1 to 4 years, being...Read More

Introduction Benzodiazepines are sedative and hypnotic medications used to treat anxiety disorders, insomnia, and also serve as an adjunct in surgical anesthesia. These drugs primarily modulate GABA receptors, the major inhibitory neurotransmitter in the central nervous system, thereby exerting a calming effect and managing symptoms effectively. When used within recommended doses and under medical supervision,...Read More

Introduction Acetaminophen, also known as paracetamol, is a widely used over-the-counter analgesic and antipyretic. While it is generally safe when used within recommended doses, acetaminophen overdose is a common cause of Acute Liver Failure (ALF),(1) leading to significant morbidity and mortality. Acetaminophen poisoning results from both acute overdose and Repeated Supratherapeutic Ingestion (RSTI), which can...Read More

Introduction Paracetamol (acetaminophen) is extensively recognized for its analgesic and antipyretic properties, and it remains a widely utilized pharmaceutical agent due to its favorable safety profile when administered within the recommended therapeutic range. However, surpassing the established safety threshold can precipitate significant adverse effects, most notably hepatotoxicity mediated by the excessive accumulation of the reactive...Read More